SUCCESSFUL TREATMENT OF TWO CASES WITH PHILADELPHIA-CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA WHO RELAPSED AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND THE TREATMENTS WITH NOVEL IMMUNOTHERAPIES AND PONATINIB

The outcomes of relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) resistant to new drugs such as tyrosine kinase inhibitors, inotuzumab ozogamicin (InO) and blinatumomab are dismal.We treated two cases of Ph+ALL resistant to these drugs that achieved long-term Pickleball Paddle Cover survival after treatment with chime

Full-fat roasted date seeds are considered an excellent source of antioxidants which can treat many diseases.The specific objectives were to investigate the effect of roasting temperature Dress Up Accessories and time on the hardness of whole seeds, moisture content of the roasted date seeds powder, DPPH radical scavenging activity, total phenolic

This paper proposes Dress Up Accessories an incremental optimization framework for verifying graph transformation systems to overcome the state space explosion (SSE).SSE refers to the exponential growth of the number of possible states in a system during its verification.The framework maps the verification problem to a search problem and incrementa

Cancer remains a significant global challenge, with escalating incidence rates and a substantial burden on healthcare systems worldwide.Herein, we present an in-depth exploration of the intricate interplay between cancer cell death pathways and tumor immunity within the tumor microenvironment (TME).We begin by elucidating the epidemiological landsc

Based on a comprehensive review and critical analysis of the literature regarding the effects of sodium bicarbonate supplementation on exercise performance, conducted by experts in the field and selected members of the International Society of Sports Nutrition (ISSN), the following conclusions represent the official Position of the Society: 546 Sup